A calorie isn't a calorie - low carbers have a thermogenic advantage."Thus, it is clear that insulin plays an important role in obesity, independent of energy intake.""Bluher et al (7) showed that the lack of an insulin receptor in fat tissue produces almost complete protection against obesity. In other words, fat-specific insulin receptor knockout mice can eat a lot of “extra calories” and still hardly gain any fat mass."http://ajcn.nutrition.org/content/83/6/1442.full
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