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Author: LorenCobb Big gold star, 5000 posts Top Favorite Fools Top Recommended Fools Feste Award Nominee! Old School Fool Add to my Favorite Fools Ignore this person (you won't see their posts anymore) Number: of 142  
Subject: ABC Movie - Fatal Contact Date: 5/10/2006 12:39 PM
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Last night (May 9), ABC aired a made-for-TV movie on avian influenza, entitled Fatal Contact. It was not too bad, on the whole, and I am sure it scared the crap out of a lot of people.

The impressions left by Fatal Contact were incorrect or distorted on a number of points:

1. Although a world-wide death toll of 350 million is possible, that is at the outer limits of influenza mortality. It was a worst-case scenario. The most-likely case scenario is much less, even assuming that a human form of the virus will have the same lethality as the existing bird form.

2. The movie assumed that a worldwide pandemic would begin literally within weeks of a mutation, and that it would hit all countries more-or-less simultaneously. Influenza has never behaved that way in all of recorded history. This was an assumption made for dramatic effect, which left a drastically incorrect impression on the viewers.

In reality, we expect that even an extremely lethal human form of avian influenza will behave much like past epidemics. It will move slowly from region to region, giving most of the world many months to prepare.

3. In the movie, the virus actually gained lethality. In the final scene, a new form has appeared in Africa, with 100% mortality. Again, this is contrary to the way viruses evolve. In general, any lethal virus is subject to enormous Darwinian selection in favor of lower mortality, for the simple reason that killing the host is a bad way to survive. For example, the Plague that killed a third of Europe in the Middle Ages is now seldom fatal, and is still visibly losing steam.

In the case of avian influenza, if it ever changes to a human-transmissable form, we can confidently expect it to lose lethality as the months and years progress. Those hit in the first wave will suffer the highest mortality, and each successive wave will be less potent.

4. Speaking of waves, the ebb and flow of the epidemic was very poorly portrayed in the movie. In real life, a community hit by lethal influenza will suffer an initial surge of the disease. Infected people will be isolated in their homes, and after a month or two the initial phase will be over. As people let down their guards, it is entirely possible (even likely) that there will be a second surge of the disease, and then a third. Later waves will be slower and less severe, until finally the average number of newly infected per infectious case drops below 1.0, and the epidemic dies out naturally.

Loren
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