UnThreaded | Threaded | Whole Thread (11) | Ignore Thread Prev | Next
Author: CultClassic One star, 50 posts Old School Fool Add to my Favorite Fools Ignore this person (you won't see their posts anymore) Number: of 41633  
Subject: Re: Pfizer-No more needles Date: 1/29/2006 9:12 AM
Post New | Post Reply | Reply Later | Create Poll Report this Post | Recommend it!
Recommendations: 2
Anyway, my question is mostly directed to those who has more indepth knowledge in this or are in the medical field. Is there a potential danger to prolonged use of inhaled insulin (such as maybe decreased effectiveness after prolonged use, etc)?

Ibarz,

The biggest concern that I have heard is the effect that the inhaled insulin may have on the lungs. People who take Exubera will have to inhale multiple doses per day for the rest of their lives. No one knows how this will affect lung function over the long term. For this reason, prudence suggests that it not be use in those with asthma, COPD, etc. The other potential problem is that while inhaled insulin may more readily gain patient acceptance, it remains to be seen whether their blood glucose control will be as good as with injectable insulin. That is the bottom-line with any diabetic therapy - will it lower the blood glucose level so that the chronic and acute complications of diabetes are avoided.

The problem with studies to approve chronic use medication is that 1-2 years simply isn't enough time and there usually aren't enough patients to assess long term consequences in large populations. This is why there is always risk with new drugs that no trial can adequately address. See Vioxx.

S
Post New | Post Reply | Reply Later | Create Poll Report this Post | Recommend it!
Print the post  
UnThreaded | Threaded | Whole Thread (11) | Ignore Thread Prev | Next

Announcements

BMW METHOD EVENTS

The 2009 BMW Method Conference has been cancelled, due to minimum attendance numbers not being met. We hope to continue the annual BMW Method Conference tradition next fall.

Learn about the first four conferences on the BMW Method Website.

The BMW Method FAQ

BMW Method Website
Annual Conference Videos and Other Resources & Services
Pencils of Promise - Back to School Drive
"Pencils of Promise works with communities across the globe to build schools and create programs that provide education opportunities for children."
Post of the Day:
Macro Economics

Heads Up, Real Estate Investors
What was Your Dumbest Investment?
Share it with us -- and learn from others' stories of flubs.
When Life Gives You Lemons
We all have had hardships and made poor decisions. The important thing is how we respond and grow. Read the story of a Fool who started from nothing, and looks to gain everything.
Community Home
Speak Your Mind, Start Your Blog, Rate Your Stocks

Community Team Fools - who are those TMF's?
Contact Us
Contact Customer Service and other Fool departments here.
Work for Fools?
Winner of the Washingtonian great places to work, and "#1 Media Company to Work For" (BusinessInsider 2011)! Have access to all of TMF's online and email products for FREE, and be paid for your contributions to TMF! Click the link and start your Fool career.
Advertisement