http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjourna...Minimal Intensity Physical Activity (Standing and Walking) of Longer Duration Improves Insulin Action and Plasma Lipids More than Shorter Periods of Moderate to Vigorous Exercise (Cycling) in Sedentary Subjects When Energy Expenditure Is ComparableOne hour of daily physical exercise cannot compensate the negative effects of inactivity on insulin level and plasma lipids if the rest of the day is spent sitting. Reducing inactivity by increasing the time spent walking/standing is more effective than one hour of physical exercise, when energy expenditure is kept constant.
http://www.businessweek.com/magazine/content/10_19/b41770712...They may well be caused by doing precisely what you're doing—sitting. New research in the diverse fields of epidemiology, molecular biology, biomechanics, and physiology is converging toward a startling conclusion: Sitting is a public-health risk. And exercising doesn't offset it. "People need to understand that the qualitative mechanisms of sitting are completely different from walking or exercising," says University of Missouri microbiologist Marc Hamilton. "Sitting too much is not the same as exercising too little. They do completely different things to the body."In a 2005 article in Science magazine, James A. Levine, an obesity specialist at the Mayo Clinic, pinpointed why, despite similar diets, some people are fat and others aren't. "We found that people with obesity have a natural predisposition to be attracted to the chair, and that's true even after obese people lose weight," he says. "What fascinates me is that humans evolved over 1.5 million years entirely on the ability to walk and move. And literally 150 years ago, 90% of human endeavor was still agricultural. In a tiny speck of time we've become chair-sentenced," Levine says. Hamilton, like many sitting researchers, doesn't own an office chair. "If you're standing around and puttering, you recruit specialized muscles designed for postural support that never tire," he says. "They're unique in that the nervous system recruits them for low-intensity activity and they're very rich in enzymes." One enzyme, lipoprotein lipase, grabs fat and cholesterol from the blood, burning the fat into energy while shifting the cholesterol from LDL (the bad kind) to HDL (the healthy kind). When you sit, the muscles are relaxed, and enzyme activity drops by 90% to 95%, leaving fat to camp out in the bloodstream. Within a couple hours of sitting, healthy cholesterol plummets by 20%.The data back him up. Older people who move around have half the mortality rate of their peers. Frequent TV and Web surfers (sitters) have higher rates of hypertension, obesity, high blood triglycerides, low HDL cholesterol, and high blood sugar, regardless of weight. Lean people, on average, stand for two hours longer than their counterparts. http://www.theglobeandmail.com/life/health-and-fitness/is-yo...You’re going to want to stand up for this. Researchers of sedentary behaviour, a burgeoning field with Canadians at its forefront, are beginning to amass a large body of evidence with one unsettling conclusion: Sitting down is killing us.For decades, hundreds if not thousands of studies have examined the relationship between our activity levels and our health. Only recently have researchers turned their attention to the consequences of sitting at a desk all day and lying on the couch all evening.The average person now spends 9.3 hours a day sitting. People who sit for six or more hours per day are 40 per cent more likely to die within 15 years compared to someone who sits less than three hours a day, even if they exercise. Obese people sit 2½ hours more each day than people of normal weight, according to data compiled by Medical Billing and Coding, a U.S.-based organization.
" Older people who move around have half the mortality rate of their peers."^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^The mortality rate of people moving around should be much less than thoseno longer moving around.Howie52
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