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Author: marsuculix One star, 50 posts Add to my Favorite Fools Ignore this person (you won't see their posts anymore) Number: of 636  
Subject: GDC-0973 - Exelixis hidden gem Date: 9/19/2012 2:32 AM
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hi fellow Fools,

as promised, here my next post regarding Exelixis

GDC-0973, Genetech/Roche's potent, selective MEK1/2 inhibitor, is used in combination with a PI3K inhibitor in the treatment of solid tumors.
References:

http://www.gene.com/gene/pipeline/status/oncology/mek/

http://www.asco.org/ASCOv2/Meetings/Abstracts?&vmview=ab...

Interesting fact: GDC-0973 is also known as XL-518 (originally developped by Exelixis !). See reference here:

http://www.medkoo.com/Anticancer-trials/GDC-0973.htm

At ESMO 2012 there will be a pivotal latebreaker presentation - LBA28 - of a phase-I trial; as this information is embargoed, the results will be available on Saturday, Sep 29, 2012, 9:15 am (Vienna time)the earliest.
I intend to make the conclusion of this latebreaker available to you asap., since I plan to attend this session

It looks like Exelixis has another hot iron in the forge...

take care, marsuculix
(I am a molecular biologist and consultant to Swiss pharmaceutical companies - I will try to dig a hole to my former university colleagues working @ Roche - may be it pays off)
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