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I would guess that "hardening of the arteries" is one factor. Hence, higher blood pressure is needed to service all parts of the body. I wonder if arteries become less flexible too as we age.

I still hold to the point of view that multiple meds controls bp while minimizing the worst side effects.

If side effects are a concern, the real experts are nephrologists who specialize in hypertension. Ask for a referral especially if your creatinine begins to rise (even a little). That indicates reduced kidney function caused by damage from high blood pressure. It's serious and another factor that reduces your life expectancy if untreated.
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