More Science By Press Release What are you basing this statement on? The post by Zoning Fool consists of ABC's coverage followed by the abstract of the research study just published in JAMA. Neither of them says that fructose--as opposed to glucose--makes people fat. The brain blood-flow studies document different effects on the brain after drinks containing either glucose or fructose. There is no effect on the hormones (leptin and grehlin) that influence hunger and satiety. Glucose directly activates the satiety centers. Fructose does not activate them. And not included in the abstract, but in a medical review I read this morning, is that the people in this randomized, blinded cross-over study reported satiety after the glucose-sweetened drink and continued hunger after the fructose-sweetened drink.What had prompted this study, done at Yale, was the desire to shed light on why hungry mice fed glucose-sweetened food show satiety, but when fed fructose-sweetened food they show continued hunger.So an interesting association does emerge linking fructose consumption to weight gain, ie, fructose leaves people still feeling hungry, so they keep eating. Obviously, fruits contain sucrose and high fruit consumption isn't associated with overweight. But looking at the prevalence of high-fructose corn syrup as a sweetener in so many foods today--as it's cheaper than glucose--and looking at the high caloric and empty nutritional values in so many of these foods, points to the problem.So rather than "science by press release," I find this "food for thought."sheila
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