Norman,
thanks for the calulations. however, a couple of corrections in market size. the number of patients requiring dialysis in the united states is currently greater than 400,000. fairly good estimates place that number at around 2 million by the year 2030.
these patients are amazingly prone to developing all types of infections; some of the most life threatening and most damaging infections are staph aureus.
additionally, many other patients who have catheters for other reasons (i.e. cancer patients receiving regular chemo injections, sickle cell patients requiring frequent transfsions) will also contribute to the patients benefitting from this potential vaccine.
overall, i think the numbers are much higher than what you have calculated above