RS - have you considered stepping back on the dosage to see if your tolerance level might be dose-related? Then slowly increase to see if you find your personal sweet spot.

Additionally, how long have you been taking the supplement? Some people adjust to certain ones after a couple of weeks. If you have only been taking it for a few days, perhaps that is a factor.

The formula, or manufacturer, of supplement, as Sheila mentioned, could be contributing as well. Fish oil, as she mentioned, is a frequent culprit of that. Some are good. Some effect the digestive system more. Or, magnesium - the oxide version is more prone to causing diarrhea than the glycinate form, for most people. Yes, I know your issue is nausea :), but it is an illustration of functions being affected by supplement form.

Or possibly, it is not so much the supplement itself as it is the fillers that are in it? Take a version that's filler-free?

For me, I note that something as simple as Carlson's Vitamin E with Mixed Tocotrienols & Tocopherols will cause some mild nausea more-so than the "plain" D-Alpha Tocopherol form of vitamin E. Taking it before I eat, rather than just after, so that I have the largest portion of my meal in my stomach, gets rid of that. The 20-odd minutes makes a difference.

If it is something that is required to be taken on a "full" stomach or "with a meal", you might find taking it with your largest meal of the day, rather than with something simple like just a slice of toast, works better.

On the topic of dosage levels - pregnenolone, for example, could fall under the anti-aging spectrum and is known to cause nausea sometimes. Some pregnenolone supplements offer 50mg dosing. There is debate if that is too high. My licensed naturopath, FWIW, only doses up to 10mg. Since it's a field for which optimal dosing is still being determined, that could be the sort of thing for which you'd cut back, monitor how you feel and get periodic blood testing to check if things are heading in the right direction, without unbalancing the rest of your endocrine system.

Also, is there anything in your regime with which the supplement could be interacting, so that the combo is causing the nausea? Or perhaps you are just taking too many supplements at once, and need to spread the dosing out more?

Maybe this new supplement is the "straw that broke the camel's back", so to speak. To pick numbers out of a hat, if your total vitamins, minerals and supplements equal, oh say - 9, you might relieve nausea with a 3-3-3 dosing (breakfast, lunch, dinner) rather than all 9 in the a.m.

Could taking ginger or slippery elm bark possibly help with it?

Just some ideas for you,

HTH,

Laura