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Salongi says

And your point is? I hope not that they believe E=mc^2 is a law and was the foundation of the Manhattan project that made it possible and that they built those machines purely by the utilization of mathematics and no other observations or input from those who would not call themselves mathematicians nor purely theoretical physicists. If it is, you are wrong.

In physics, a law is an equation or rule that is experimentally reliable and supported by theory. e=mc^2 is a law by that definition.

No serious person claims that it was the "foundation of the Manhattan Project," but it is the origin of the certain knowledge that enormous energy could be released by nuclear fission.

Many of the major contributors to the Manhattan Project, such as Feynman and Fermi, were both theoretical and experimental physicists. There were also plenty of mathematicians.
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