Message Font: Serif | Sans-Serif
No. of Recommendations: 0
Thanks for your wisdom regarding the company's financial history. I will have to dig into those a bit more...and learn more about technical aspects of businesses in general.

One point regarding the placebo effect: CFS is known to be treatment-resistant. In fact, in 2005 a meta-analysis of treatment trials for CFS found that patients' placebo responses were lower than expected relative to most medical conditions (see

The meta-analysis likely drew from some good and some mediocre studies, but its findings are consistent with physicians' experience treating CFS, and with the fact that CFS is chronic.

Most well-planned treatment studies inevitably are able to find some weak or moderate improvements with the drug(s) - you know the sort, they use all sorts of pre- and post-test measures and scales, document whatever changes happen to be statistically significant, and conclude that the drug helps manage the disease, without curing it, and that future study is needed. Ampligen is the only drug I'm aware of that has produced complete and sustained recoveries in CFS patients, followed by long-term remissions when the drug is withdrawn and improvements when it's resumed. Not to mention the fact that there is a strong theoretical basis for why it works, regarding Rnase L and the antiviral pathway being upregulated in patients with CFS.

*Think about it for a minute.* There are currently no drugs formally approved to treat CFS. Although many off-label drugs can help fight fatigue, none of them really cure the condition. Ampligen, the only pending CFS drug for FDA approval I'm aware of, works by fixing a specific mechanism of the immune system that's off in CFS, but not in other conditions (at least, not in other non-viral diseases).
Print the post  


Live Video Event Monday!
The GP team is hosting a live video event on Monday at 4 p.m. ET. Don't worry if you can't make it — we'll have a replay and a transcript. Click for more!
When Life Gives You Lemons
We all have had hardships and made poor decisions. The important thing is how we respond and grow. Read the story of a Fool who started from nothing, and looks to gain everything.
Contact Us
Contact Customer Service and other Fool departments here.
Work for Fools?
Winner of the Washingtonian great places to work, and Glassdoor #1 Company to Work For 2015! Have access to all of TMF's online and email products for FREE, and be paid for your contributions to TMF! Click the link and start your Fool career.