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The facts are that topical forms of tetracycline and other antibiotics are widely available now. It's been known for several decades that very low oral dosage (250 mg once daily or every other day) work in some cases of acne and acne rosacea. This is such a low dosage that some feel the beneficial effects may be due to a non anti microbial action. There is absolutely nothing new about this, it's just that there has never been a formal study done before. And the role of bacteria in acne is not 100% clear since there are no good animal study models. Minocycline seems to work a bit better than other tetracyclines. The moat in this one is non existent.
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