the folk who develop a crapped out liver due to obesity related fatty liver disease. I reckon pills that work (side effects included) might be a better trade off.

Fatty liver disease! Hadn't heard of that one - I generally get educated about diseases one at a time, whenever somebody in my family comes down with one.

The Internets says that rapid weight loss is one potential cause of fatty liver disease. So watch out, it'll get you coming and going.