Well, I don't recall having said that, but it is true. I can't begin to estimate the number of my "great ideas" that turned out to be flat out wrong! That is the way creative science works. Most hypotheses get shot down soon after the data starts to come in.

One of my husband's former mentors.....the late Ros Yalow, Nobel Laureate......routinely asked the question "What did you do wrong?" at any research-in-progress meeting. This was regardless of whether any data was confirmatory or otherwise (i.e. always look for alternatives to your hypothesis.....turn it upside down)

BTW, this is the Yalow of Yalow & Berson fame oft quoted by Gary Taubes (and mentioned multiple times in GC, BC) as asserting that it's all about the insulin stoopid(or something like that) A bit of a hoot, really, as they weren't obesity researchers or looking at any effects of insulin but actually developed a radioimmunoassay that detected proteins. That's what she got the Nobel Prize for. The first protein happened to be insulin.....it couldda been trypsin or gastrin or CCK etc. etc.