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But statins affect a number of other metabolic pathways. It is quite possible that the dramatic effects of statin protection against heart attacks are a result of these other pathways and not due to the effects on cholesterol levels.However, it is proposed that statins have cardiovascular effects beyond their ability to lower cholesterol, possibly via recruitment of phosphatidyl inositol 3-kinase (PI3K) and the serine/threonine kinase, Akt. This signaling pathway has recently been linked to growth factor-mediated reperfusion salvage.http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12575984&dopt=AbstractOleDoc
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