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https://www.cdc.gov/flu/professionals/acip/2021-2022/acip-ta...

All manufacturers are making the same quadrivalent vaccine for 2021-22. So no difference in terms of which versions of influenza are covered. Previous years, only the high-dose was quadrivalent while standard vaccines covered only three versions (not all the same, sometimes).

It seems the only difference between a regular dose and a high dose might be a slightly larger dose of the same vaccine.

It seems that way, as only the Sanofi High-Dose is at 0.7ml, which is specific to age 65+.

But the Seqirus is also for those 65+ and it is only 0.5ml. With all the others, 0.5ml is a standard flu vaccination for everyone age 18 and up--with no upper age limit specified for them except the first one on the list (which specifies up to age 64 for the 0.5ml dose).

The nasal flu vaccine specifies up to age 49, which is the last flu vaccine on the list.
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