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No. of Recommendations: 4
Hi Mark:

Thanks for posting the information on VRTX and ELN, both look very good for inclusion in KARB and KARM respectively.

Don't worry, and don't be confused, biotech does not fit into the RB, RM or GG criteria well at all, but we can use elements of those investing philosophies to help us decide whether or not biotechs are good investments.

Biotechs and pharmas never can get sustained advantage, they get that government-allowed monopoly through patent protection. As you know the FDA can giveth and the FDA can also taketh away.

What we want in a biotech are some current products or ones in phase III trials, a very strong pipeline, excellent management, strong R&D spending compared to revenues, and products that are targeted to as big a market as possible. A cure for obesity or the common cold would be great!

Thanks for taking the time to repost your great research here.

Erick
(xerohype)

------

Here are some resources I posted in preparation for the biotech seminar, and then later for the biotech seminar grads board.

Biotech TMF Links

Zeke Ashton's Foolish Biotech Investment Checklist
1. Successful products on the market
2. A deep product pipeline with late-stage candidates
3. Drugs and candidates that target large or underserved markets
4. Partnerships and marketing agreements with blue-chip drug manufacturers
5. Research & development spending
6. Enough cash to fund operations for two years
7. Experienced management
8. Favorable Foolish financial analysis

Zeke Ashton's Foolish Biotech Investment Checklist Articles
Part I
http://www.fool.com/research/2000/foolsden000613.htm
Part II
http://www.fool.com/research/2000/foolsden000615.htm
Part III
http://www.fool.com/research/2000/foolsden000620.htm


http://www.fool.com/news/foth/2000/foth000929.htm
FOOL ON THE HILL: An Investment Opinion
When the FDA Says No
Shareholders of fledgling biotech drug maker Cell Pathways watched the stock collapse this week when the FDA rejected the company's application to market cancer drug Aptosyn. Investors who examined the depth of the company's drug candidate pipeline, and whether it had cash or alliances with big drug makers to survive hard knocks, would have known the risks.
By Tom Jacobs (TMF Tom9)
September 29, 2000

To invest in a drug company, you need to know two things at a minimum:

1. Does the company have enough drug candidates in its pipeline to compensate for clinical failure or FDA rejection of one or more?

2. If currently unprofitable, does the company have enough cash and big drug maker partners to survive bad news?


Biotechnology Crash Course by Zeke Ashton (TMF Centaur)
July 18, 2000
http://www.fool.com/Research/2000/foolsden000718.htm
For those interested in getting up-to-speed as quickly as possible, here are some books, magazine articles, and research documents that offer excellent information for individual investors.




Rule Breaker:

Tissue Engineering
http://www.fool.com/portfolios/rulebreaker/2000/rulebreaker000929.htm
http://www.fool.com/portfolios/rulebreaker/2000/rulebreaker000928.htm

Lancet Tissue Engineering Review
http://www.thelancet.com/newlancet/any/supplements/vol354s1/body.article8.html

Finding Biotech Rule Breakers
http://www.fool.com/portfolios/rulebreaker/2000/rulebreaker000914.htm
http://www.fool.com/portfolios/rulebreaker/2000/rulebreaker000913.htm

HGSI Breakdown
http://www.fool.com/portfolios/rulebreaker/2000/rulebreaker000828.htm
http://www.fool.com/portfolios/rulebreaker/2000/rulebreaker000829.htm
http://boards.fool.com/Message.asp?id=1400043000215000

MLNM Breakdown
http://www.fool.com/portfolios/rulebreaker/2000/rulebreaker000814.htm
http://www.fool.com/portfolios/rulebreaker/2000/rulebreaker000815.htm

RB Biotech Investing Chat
http://www.fool.com/specials/2000/sp000705.htm
http://www.fool.com/specials/2000/sp000705a.htm

MLNM CEO interview
http://www.fool.com/specials/2000/sp000322levin.htm

HGSI CEO interview
http://www.fool.com/specials/2000/sp000306hgsi.htm

CRA President interview
http://www.fool.com/specials/1999/sp991208interview.htm

RB CRA Buy Report
http://www.fool.com/portfolios/rulebreaker/trades/rulebreakertrade_cra991216.htm

RB AMGN Buy Report
http://www.fool.com/portfolios/RuleBreaker/Positions/RuleBreaker_amgn.htm
AMGN RB update 6/00
http://www.fool.com/portfolios/rulebreaker/2000/rulebreaker000602.htm
AMGN as RM
http://www.fool.com/portfolios/rulemaker/1999/rulemaker991206.htm

Biotech Education
http://www.fool.com/portfolios/rulebreaker/2000/rulebreaker000216.htm

R&D a Key to Biotech
http://www.fool.com/portfolios/rulemaker/2000/rulemaker000128.htm

FOTH Investing in biotech
http://www.fool.com/news/1999/foth991221.htm

Biotech Bubble? By Tom Jacobs (TMF Tom9)
August 25, 2000
http://www.fool.com/news/2000/biotech000825.htm

Amgen (AMGN)
By Zeke Ashton (TMF Centaur)
http://www.fool.com/research/reports/amgn.htm

U.S. OKs Human Embryo Research By Tom Jacobs (TMF Tom9)
August 23, 2000
http://www.fool.com/news/foolplate/2000/foolplate000823.htm

Myriad Genetics Reports By Tom Jacobs (TMF Tom9)
August 22, 2000
http://www.fool.com/news/foolplate/2000/foolplate000822.htm

Biogen Widens Pipeline By Tom Jacobs (TMF Tom9)
August 18, 2000
http://www.fool.com/news/2000/bgen000818.htm

Geron Reports By Tom Jacobs (TMF Tom9)
August 15, 2000
http://www.fool.com/news/2000/gern000815.htm

Ways to Invest in Biotech by Jeff Fischer (TMF Jeff)
July 5, 2000
http://www.fool.com/portfolios/rulebreaker/2000/rulebreaker000705.htm

Corning Muscles in on DNA Chips By Tom Jacobs (TMF Tom9)
September 14, 2000
http://www.fool.com/news/2000/glw000914.htm

Human Genome, Genzyme Buy Smart By Tom Jacobs (TMF Tom9)
September 11, 2000
http://www.fool.com/news/foolplate/2000/foolplate000911.htm

Lilly Trades Biotech Deals By Tom Jacobs (TMF Tom9)
September 6, 2000
http://www.fool.com/news/2000/lly000906.htm

Amgen Blood Feud Nears End By Tom Jacobs (TMF Tom9)
September 5, 2000
http://www.fool.com/news/foolplate/2000/foolplate000905.htm

Biotechnology Web Sites

About http://www.biotech.about.com/
Biotech/Biomedical

Bio http://www.bio.com/
Distributed on-line community supporting the life sciences

BioCompare http://www.biocompare.com/
The Consumer Guide for the Life Scientist

Biofind http://www.biofind.com/
Insight for the biotech industry

BioInformatics, Inc. http://www.bioinfoinc.com/
Websites for Biomedical Marketing Professionals

Bioportfolio http://www.bioportfolio.com/
Jobs, corporate profiles & more ...

BioSage http://www.biotechsage.com/
Analyses, interpretations, news, company developments, commentaries

BioSpace http://www.biospace.com/
Global hubsite for the like sciences

Biovista http://www.biovista.com/
Biotechnology corporate intelligence products and services

Bioworld http://www.bioworld.com/
Worldwide Biotechnology news and information source

DoubleTwist http://www.doubletwist.com/
Integrated genomics portal

Genetic Engineering News http://www.genwire.com/
Bioindustry News Publication

Labpuppy http://www.labpuppy.com/
Your "Retriever" for Sector & Investment Information

Pharma http://www.phrma.org/
Represents the country's leading research-based pharmaceutical
and biotechnology companies

Recombinant Capital http://www.recap.com/
The online magazine of biotechnology industry analysis

The Scientist http://www.the-scientist.com/
The News Journal for the Life Scientist

Trends in Biotechnology http://journals.bmn.com/
Extensive resource of key life science journals

Yahoo Biotechnology News http://biz.yahoo.com/news/biotechnology.html
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