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HIV patients have abnormal fat distribution at baseline, resulting in accelerated coronary disease as well. I'd be curious if they could do a large (couple thousand) patient study of egrifta vs placebo and demonstrate a decrease in ACS or mortality. THAT'S the money shot. Also, its incredibly costly to run that sort of trial.

Sadly, egrifta has been around for 8+ years and still <100m sales and theratech either hasnt thought of doing such a trial, or it wouldnt work. The NASH play is certainly intriguing, but it's not for me; I have to trust a management team to push and show a vision for me to invest. Not saying THERF may not be a profitabl trade, but its not for me.
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