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No. of Recommendations: 0
It is up to 20% on revenue. Last year they’re royalty on Spinraza was 12.5% of revenue, which I believe must have equated to around 40% of net profit. Sales were around $900 million and the orphan drug manufacturers usually bring about 25-30% to the bottom line. And, IONS has no associated expense related to their payment other than taxes.

Some our different levels of interest are based on the fact that I don’t like the binary nature of biotech. That is part of why IONS appeals to me. Much more interested to understand if this is a stock that at some point could deliver 20-25% for several years.

My only real concern remains the effectiveness of their drugs compared to any competitors. The drugs work, the safety issues seem to be under control and the drugs currently in the later stages are not even newest generation.

I don’t know. I said I was going to hold my 100 shares and then I bailed.
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